Increasing impacts from hazards worldwide, including Sweden, have prompted international efforts to promote the development of national strategies for disaster risk reduction (DRR) and resilience to reduce associated impacts and support sustainable development. The development of such strategies is global target E of the Sendai Framework for DRR 2015-2030, which was adopted in 2015 by Sweden and other UN member states. An increasing understanding of the need to address the underlying causes of risk has led to demands for more coherence in strategies that focus on DRR, climate change adaptation, and sustainable development. The Sendai Framework, Paris Agreement on Climate Change, Agenda 2030, and the Sustainable Development Goals (SDGs) promote such strategies. MSB is the Swedish national focal point for the Sendai Framework and thus commissioned to drive its implementation in Sweden. The overall purpose of this study was to support MSB in the implementation of the global target E of the Sendai Framework for DRR. The specific aim was to provide knowledge and recommendations for decision-making. This includes the analysis of the relevance and scope of developing a national strategy for DRR and resilience. The study also identifies drivers and barriers for creating policy coherence and local-level support. In fact, it addresses what to consider in developing a national and local strategies and provides information about how to achieve coherence with current laws and strategies. Furthermore, the study addresses the challenges of meeting UNDRR’s ten criteria for DRR strategies and four priority areas as well as the importance of selecting good indicators. Apart from the local context and conditions, it considers lessons learned from six other European countries.