This study is a knowledge review of scientific research, development and innovation in the area of protection of first responders at incident sites. The specific aim of the study was to search for research connected to three capability gaps identified within the international cooperation International Forum to Advance First Responder Innovation (IFAFRI). The three capability gaps include the ability to, in real time; 1) in real-time know the location of first responders and their proximity to risks and hazards, 2) in real-time detect, monitor, and analyze passive and active threats and hazards at incident scenes and 3) to rapidly identify hazardous agents and contaminants. The study was divided into three parts; a review of scientific research, workshops with subject matter experts (SMEs) at the Swedish Defence Research Agency, FOI, and a review of innovations and products available on the Swedish market.